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Disclosures: Lily Dara: Intercept Pharmaceuticals: Consultant, Intercept Pharmaceuticals: Grant/Research Support, Paola Nicoletti: Nothing to Disclose, Chaudry Majeed: Nothing to Disclose, Andrew Dellinger: Nothing to Disclose, David Kleiner: Nothing to Disclose, Mahmoud Mohamed: Nothing to Disclose, Tatyana Kushner: Gilead: Grant/Research Support, Gilead: Advisor, GSK: Advisor, Eiger: Advisor, Mohammed Umair Masood: Nothing to Disclose, Raj Vuppulanch: Eli Lilly: Grant/Research Support, Echosens: Consultant, Zydus THerapeutics: Grant/Research Support, GSK: Consultant, MERCK: Advisor, Takeda: Grant/Research Support, Huiman Barnhart: Nothing to Disclose, Jiezhun Gu: Nothing to Disclose, Herbert Bonkovsky: Nothing to Disclose 1252 CO-ADMINISTRATION OF ALCOHOL, RITONAVIR AND LOPINAVIR AFFECTS EXPRESSION OF THE SET CHEPERONE PROTEIN IN HEPATOCYTES AND MONOCYTES AND HIV-1 INFECTIVITY IN VITRO Liting Chen 1 Marina Kaypaghian 1 Cheng Ji 1 , 1 University of Southern California Background: Combined use of alcohol and antiviral drugs is known to cause cellular stress and organ injury raising peoples vulnerability to virus infection

No, the proportion of lean mass lost with GLP-1 medications (approximately 2040% of total weight loss) is similar to other weight loss interventions including dietary restriction and bariatric surgery
Supporting Data: According to some studies, a high-fiber diet is associated with an increase in GLP-1 secretion, contributing to improved insulin sensitivity and satiety
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Japan presents a further variation on the access theme