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Grill D, Tausz T, De Kok LJ (2001)

Epithalamin had demonstrated bioregulatory activity in earlier experimental gerontology research, and Epitalon was developed to provide a chemically characterized, reproducible molecular tool for investigating its underlying mechanisms

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These were the endothelium damaging agents, i.e., alcohol [32] or lithium [31], bile duct occlusion (acute pancreatitis) [29], organs and vessels compression (intra-abdominal hypertension) [31]

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