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Most patients reach their maintenance dose over 16 to 20 weeks, increasing by 0.25 mg each week until arriving at a therapeutic level between 1.0 and 2.4 mg weekly

Long-term success requires combining medication with sustained dietary and lifestyle changes to prevent rebound

For example, stable blood sugar levels mean the body doesnt experience sudden highs and lows, which can be stressful

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Potential contribution of hypoxia-inducible factor-1, aquaporin-4, and matrix metalloproteinase-9 to blood-brain barrier disruption and brain edema after experimental subarachnoid hemorrhage