Li W, Zeng Q, Liu Y, Zhao X, Chen X, Yang W
Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions
Just as importantly, the addition of extra ingredients creates a formulation that differs from the branded products, which compounders may use as a legal justification to avoid producing an outright copy of a brand-name drug.Recall Initiation Date: May 21, 2025Link: FDA Enforcement Report Wegovy (semaglutide) Company: Cardinal Health (drug distributor)Company Location: Dublin, OhioManufacturing Location: Novo Nordisk, Bagsvaerd, DenmarkScope: 2.4 mg/0.75 mL, 4 Single-Dose Prefilled Pens per Carton (48 cartons)Drug Description: Weight loss treatmentRecall Reason: Product was not stored under labeled storage temperature requirements due to a shipping error involving a Cardinal Health distribution center
Visual check: Solution should be clear, colorless (unless B12 is present), and free of visible particles
Clearly labelled for laboratory identification
Its global prevalence is high, affecting roughly 30% of the population, and has shown an alarming 50.4% relative increase between 1990 and 2019 (3)