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Calcium channel blockers (CCBs) are ineffective

Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion

Mol Psychiatry

In sum, abnormalities in mitochondrial function and content within the placenta are linked to compromised placental energetics and elevated oxidative stress, ultimately contributing to adverse pregnancy outcomes

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A genetic implication of HGF and MET in the development of brain emerges from the literature, and various alterations in the HGF-MET pathway correlate with features of some NDDs such as ASD, schizophrenia, and non-syndromic hearing loss