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And some people are more affected by one or the other more than others

Free Radic Biol Med 146:7991 Li Y-Q, Chen Y, Jiang S-Q, Shi Y-Y, Jiang X-L, Wu S-S, Zhou P, Wang H-Y, Li P, Li F (2021) An inhibitor of NF-B and an agonist of AMPK: network prediction and multi-omics integration to derive signaling pathways for acteoside against Alzheimers disease

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Specifically, NAC exponentially increases the production of specialized detoxification enzymes known as Glutathione S-transferases (GSTs)