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Celastrol, a widely used antioxidant drug, can reduce ROS accumulation by upregulating the Nrf2/GPX4 axis, thus significantly inhibiting ferroptosis of neurons and oligodendrocytes, thereby promoting the recovery of spinal cord tissue and motor function in rats with SCI

10.1016/j.fitote.2016.02.001 60 LiuY

In an interview, Lurie said allowing peptides on the market without clinical testing poses a profound threat to FDAs decades-old system for vetting drugs

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