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retatrutide phase 2 nejm 2023 obesity trial jastreboff

retatrutide phase 2 nejm 2023 obesity trial jastreboff 🚨Breaking: Retatrutide's first 3 T2D data just dropped. ▸ A1C: −2.0% at 40 weeks ▸ Weight: −36.6 lbs (−16.8%) at 12 mg ▸ No weight loss plateau — curve still descending Retatrutide: FDA approval time, trial

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Description

Mouse breeders readily recognize pale animals, and have developed anemic stocks with various mutations

retatrutide phase 2 nejm 2023 obesity trial jastreboff Breaking: Retatrutide's first 3 T2D data just dropped. A1C: 2.0% at 40 weeks Weight: 36.6 lbs (16.8%) at 12 mg No weight loss plateau curve still descending Retatrutide: FDA approval time, trial

For perspective on where this lands against the field (placebo-adjusted weight loss): Type 2 diabetes TRANSCEND-T2D-1 (n = 537, 40 weeks) Published simultaneously in The Lancet

retatrutide phase 2 nejm 2023 obesity trial jastreboff Breaking: Retatrutide's first 3 T2D data just dropped. A1C: 2.0% at 40 weeks Weight: 36.6 lbs (16.8%) at 12 mg No weight loss plateau curve still descending Retatrutide: FDA approval time, trial

Vercellini P, Buggio L, Berlanda N, Barbara G, Somigliana E, Bosari S

retatrutide phase 2 nejm 2023 obesity trial jastreboff Breaking: Retatrutide's first 3 T2D data just dropped. A1C: 2.0% at 40 weeks Weight: 36.6 lbs (16.8%) at 12 mg No weight loss plateau curve still descending Retatrutide: FDA approval time, trial

Weekly injections are effective but inconvenient

retatrutide phase 2 nejm 2023 obesity trial jastreboff Breaking: Retatrutide's first 3 T2D data just dropped. A1C: 2.0% at 40 weeks Weight: 36.6 lbs (16.8%) at 12 mg No weight loss plateau curve still descending Retatrutide: FDA approval time, trial

KPV An anti-inflammatory peptide studied for gut barrier integrity, with potential applications in inflammatory bowel conditions

retatrutide phase 2 nejm 2023 obesity trial jastreboff Breaking: Retatrutide's first 3 T2D data just dropped. A1C: 2.0% at 40 weeks Weight: 36.6 lbs (16.8%) at 12 mg No weight loss plateau curve still descending Retatrutide: FDA approval time, trial

Lee K, Won HY, Bae MA, Hong JH, Hwang ES

retatrutide phase 2 nejm 2023 obesity trial jastreboff Breaking: Retatrutide's first 3 T2D data just dropped. A1C: 2.0% at 40 weeks Weight: 36.6 lbs (16.8%) at 12 mg No weight loss plateau curve still descending Retatrutide: FDA approval time, trial
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