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Description

Preclinical studies have shown that large doses of GLP-1RAs can reduce lipid deposition and plaque volume on the aortic surface of hyperglycemic mice via an AMPK-independent action in streptozotocin (STZ)-induced hyperglycemic and hyperlipidemic mice or type 1 diabetic rats [55]

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Regarding U251 cell line exometabolome, the most important metabolites (Fig

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In the Colao et al

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Matsumoto D, Sato K, Gonda K, Takaki Y, Shigeura T, Sato T, Aiba-Kojima E, Iizuka F, Inoue K, Suga H, Yoshimura K

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& Yamauchi, K

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Also discussed are dietary and lifestyle strategies to manage histamine intolerance and provide guidance on supplements and lab testing to optimize histamine metabolism

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