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Estrogen plays an important role in maintaining the health of the vaginal and urethral tissues

According to statistics, as of mid-2025, there were approximately 277 obesity drugs in development globally, but the vast majority were still in preclinical or Phase I stages

Pharmacol Res 173:105912

The comparison of the number of OEs between the three groups was inconclusive due to the small effect size associated with the occurrence of OEs and the resulting lack of statistical power

There were 12 SAEs (11 SAEs and one SUSAR) in the trial (Table 4)

The discussion included research priorities for adjunctive (non-insulin) therapies for people with T1D and their healthcare providers