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5961 The most prominent GLP-1R signaling pathway stimulates adenylyl cyclase, leading to increased concentrations of cyclic adenosine monophosphate (cAMP) and the subsequent activation of protein kinase A (PKA)

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464 In addition, topical rapamycin treatment reduces the levels of aging markers in aged skin tissue and improves skin health (NCT03103893)

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10.1111/j.1472-8206.2007.00471.x 7 BallesterB.MilaraJ.CortijoJ