This is one of the few interventions where we truly see meaningful collagen stimulation clinically, especially for diffuse volume loss
Dont Forget Folate Supplementation Folate is a critical nutrient for all women planning to become pregnant
The mechanisms potentially contributing to cardiovascular protection may include effects on weight, glycemic control, blood pressure, and possibly direct effects on vascular inflammation and lipid metabolism, though these mechanisms remain under investigation
Ferr, P
Moreover, the percentage of participants in clinical trials who stopped the treatment due to AE was 515% with most of the new agents, and this percentage was up to 2030% with some of GLP-1/glucagon RA in phase 2 trials so a considerable proportion of people may not be able to tolerate the new obesity pharmacotherapies or may be unable to titrate them to the higher and most effective doses
In some cases, patients may be transitioned to an alternative medication that is safe for pregnancy and can be used to help manage their metabolic health during pregnancy