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Because only small volumes can be administered intranasally (approximately 100150 L per nostril), achieving therapeutic doses often requires highly concentrated formulations and therefore favours potent drugs (Chung et al., 2023

GbE + PTZ protective group was given 100 mg/kg EGb for 17 days, followed by 40 mg/kg PTZ for other 17 days

Once produced by your body, Carnitine is stored in your heart and brain