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In the head-to-head SURMOUNT-5 trial (NEJM 2025) tirzepatide produced larger mean body-weight reduction than semaglutide (20.2% vs 13.7% at 72 weeks), although semaglutide carries the broader cardiovascular- and kidney-outcomes dataset to date

[DOI] [PMC free article] [PubMed] 290.Thomas MC

Technical assistance of Sofie De Bruyckere, Nathalie Van Rysselberghe and Sophie Callens is greatly acknowledged

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I make sure to get seven to nine hours every night, where it can impact my mood