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Expectations have gotten so high that Novo Nordisks stock actually dropped when it announced that their drug candidate CagriSema (a mix of semaglutide with the experimental drug cagrilintide) only helped people lose 22% weight in a recent trial, rather than the 25% expected

Curi R, Lagranha CJ, Doi SQ, et al

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An Increase in the Akkermansia Spp

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Synchrotron fluorescence imaging of individual mouse beta-cells reveals changes in zinc, calcium, and iron in a model of low-grade inflammation