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Biochem Med 2008;18:331-41

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Upon hyperglycemia and sepsis resolution, a basal-bolus insulin therapy was initiated (total daily insulin requirement 0.4 unit per kg of BW, approximately 26 U/day) yielding a progressive improvement of daily glucose profiles

Smaller, more frequent meals (4-5 per day) often work better than trying to hit calories in 2-3 large meals