All animal procedures took place at the University of Texas at Arlington and were approved by the Universitys IACUC
Metformin works on insulin sensitivity and glucose production
Try a cash pay medication: Some medications are not covered by insurance, but may be cheaper overall
Some plans may offer coverage, but it varies and often requires prior authorization
Patients should be counseled about the risk of dehydration and potential acute kidney injury with severe gastrointestinal symptoms, and the need to temporarily hold medication and seek care if severe vomiting or diarrhea occurs
This could be because GLP-1s change taste perception, decrease reward seeking or because high-fat fried foods can cause nausea, and when someone experiences severe nausea in association with a food, they tend to avoid that food quite rigorously afterwards (known as conditioned taste aversion)