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Although it is often referred to as an amino acid, structurally it is more similar to a vitamin-like substance
Caffeine, through A 1 and A 2A receptor antagonism, is involved in the control of synaptic transmission and plasticity, which may be related to its neuroprotective effect [95]
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While previous research has firmly established its capacity to ameliorate hepatic steatosis, likely by activating the hepatic AMPK signaling pathway to promote fatty acid oxidation and inhibit lipogenesis, and exerting anti-inflammatory effects by suppressing cytokines such as TNF- and IL-6 16 , the present study provides a more unified mechanistic explanation for this
