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[DOI] [PubMed] [Google Scholar] 178.Chai S., Yu S., Yang Z., et al

Apart from the potent GH-releasing action, ghrelin has other actions including stimulation of lactotroph and corticotroph function, influence on the pituitary gonadal axis, stimulation of appetite, control of energy balance, influence on sleep and behavior, control of gastric motility and acid secretion, influence on exocrine and endocrine pancreatic function as well as on glucose metabolism, cardiovascular actions and modulation of proliferation of neoplastic cells, as well as of the immune system

These two research directions overlap in the literature but represent distinct lines of inquiry, each rooted in a different aspect of the peptides mechanism

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The physiological changes accompanying weight lossincluding alterations in fluid balance, electrolyte levels, and dietary intakemay indirectly contribute to cramping