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Our findings may indicate reduced CPT-I activity in the patient group, which is essential for the -oxidation of long-chain fatty acids, facilitating their conversion into acylcarnitines for transport from the cytosol into the inner mitochondrial matrix [17,18]

In one trial, the 25 mg dose led to an average 7% weight loss , while the 50 mg dose led to an average of 15% weight loss

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Conclusion This study is the first to identify C10:2 as a potential biomarker for PVR in PH and to elucidate the novel biological mechanism by which C10:2 facilitates multiple cellular phenotypes to promote vascular remodeling

Sci Rep (2021) 11:18156