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In some cohorts, more than 70% of patients report significant pain reduction within a few months. Sciatica is a symptom, not a disease, so how long it lasts depends on the underlying causesuch as disc herniation, spinal stenosis, bone spurs, or degenerative disc disease

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Scholten D, Trebicka J, Liedtke C et al (2015) The carbon tetrachloride model in mice