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Participants were eligible if we had the following data available at the start of treatment (day 0) and at the follow-up after one year (365 14 days): Before treatment initiation: sex, age (years), body weight (kg), waist circumference (cm), height (cm), body mass index (BMI), systolic and diastolic blood pressure, heart rate, and Edmonton Obesity Staging System (EOSS) score

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Immunosenescence contributes to: Increased infection risk Slower recovery from illness Reduced vaccine responsiveness Chronic inflammation Greater susceptibility to age-related diseases At the same time , many older adults experience "inflammaging," a state of persistent low-grade inflammation that accelerates biological aging