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Rogers syndrome, or thiamine-responsive megaloblastic anemia (TRMA), is caused by a defect in the active transport of thiamine (THTR1) in various cells, in particular this defect causes pancreatic -cell apoptosis and insulin secretion impairment, leading to the development of insulin-dependent diabetes (122, 123)
M., Minah, G
What metrics will justify future funding or adoption
(PubMed) If AOD-9604 re-enters mainstream clinical availability through compliant channels, the most responsible use-case will likely be: carefully selected patients, realistic expectations, body composition focus, and as an adjunctnot a centerpiece
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