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Meta-analyses using data from randomized, controlled CV outcomes trials showed that GLP-1 RAs were associated with a significant reduction in the risk of three-component major adverse CV events (CV death, non-fatal myocardial infarction and non-fatal stroke), and a significant reduction in the risk of fatal or non-fatal stroke, versus placebo in addition to standard-of-care (SoC) treatment [13, 14]

PTP1B inhibitors for type 2 diabetes treatment: a patent review (2011 - 2014)

Food-effect bioavailability and fed bioequivalence studies

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Specifically, DSIP decreases basal corticotropin (ACTH) levels and blocks its release under stress