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Given that nicotine easily diffuses from the dermis to the bloodstream, acute nicotine exposure by e-liquid spilling (5 mL of a 20 mg/mL nicotine-containing refill is equivalent to 100 mg of nicotine) can easily be toxic or even deadly [8]

Previous Surgeon Generals reports (summarized below) concluded that there is a relationship between smoking and body weight in adults, but this report focuses more specifically on the relationship between smoking and body weight in adolescents and young adults

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Everybody says, Well, you sued over cigarettes and theres tobacco in that. I said, I sued the cigarette industry