As discussed in section V.B.8
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Side Effects and Safety Side effects Across preclinical studies and the small human trials published to date (~28 subjects across pilot studies), the reported adverse events stay limited: Mild injection-site irritation (rare) No systemic toxicity at therapeutic doses in published reports Oral administration: mild GI upset in sensitive individuals No immunosuppression, hormonal disruption, or metabolic side effects have been observed
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In fact, a 2021 study found that higher levels of vitamin B12 may be linked with better sleep quality and decreased use of sleep medication
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