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Description

In contrast, short-chain fatty acids at least up to octanoate can permeate the inner mitochondrial membrane in a non-esterified state, and they are activated to their CoA-derivatives in the mitochondrial matrix for use in energy-dependent mitochondrial processes

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The most defensible statement is narrow: severe deficiency of methionine and choline impairs hepatic fat export and causes steatosis the classic methionine-choline-deficient (MCD) diet reliably induces fibrosing steatohepatitis in rodents [4] [5]

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