precursor to glutathione production Glutathione: a review on biotechnological | Applied Microbiology and Biotechnology Glutathione - Wikipedia

GHK-Cu is a copper peptide

Contraindications: Active uveal inflammation Most cases of angle-closure glaucoma , due to the possibility of increasing angle block Hypersensitivity to the active or inactive ingredients Side Effects: Retinal detachment has been reported in a few cases Stinging, burning, lacrimation Iris cysts may form Lens opacities Cardiac irregularities Pharmacokinetics: Administered in eye drops to patients with glaucoma ) Forms an irreversible covalent bond with the ACh binding site on cholinesterase (duration of action is ~100 hrs Drug Interactions: Potentiates other cholinesterase inhibitors such as succinylcholine or organophosphate and carbamate insecticides Patients undergoing systemic anticholinesterase treatment should be warned of the possible additive effects References: Merck Manual Professional Edition (2026): Medications Used to Treat Glaucoma

In combination with the AIE property, TPE-DCV exhibits high selectivity GSH over other biological thiols, e.g

Oxidatively induced DNA damage: mechanisms, repair and disease

Am J Path 1999;155:198592

doi: 10.1089/ars.2014.5933 29 PupoEPlaAFAvanzatoDMocciaFCruzJETanziFet al