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Concurrent administration with cysteine or N-acetylcysteine enhances hepatic sulfate production, which could alter acetaminophen metabolism and should be considered when treating patients with chronic pain requiring frequent analgesia

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ROS influence proteasomal, lysosomal, and mitochondrial function, which, in turn, regulate the cellular response to oxidative damage (Cook et al., 2012)

Pancreatitis represents a rare but serious adverse reaction

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