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History was taken and Disease activity had measured by (DAS28-ESR) Disease activity score 28 ESR from each patient and Ten, milliliters of blood were withdrawing from each control and patient, used for measurements of the GR Result : In studying of Glutathione reductase (GR) enzyme there are high enzyme concentration in human serum patient with Rheumatoid arthritis than the healthy control subject serum ( =10.622 5.213, =6.522 1.867 ng/ml) respectively with highly statically significant (T-Value 6.58, P- Value 5.1 that mean is patient with high disease activity [30-33]

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For a related structural classification guide, see: Is Reta a Steroid? Structural Classification & Mechanism of Action