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On April 28 the FDA reaffirmed three concerns first issued in March about compounded GLP-1 drugs

Nausea, vomiting, constipation, stomach pain, and other digestive symptoms are higher-risk situations

The 68-week STEP 1 trial showed 14.9% mean body weight reduction at 2.4mg, compared to retatrutide hitting 17.5% at just 24 weeks with the 12mg dose

Some patients achieve their goals at lower doses

Here, we reviewed the therapeutic effects and possible mechanisms of action of GLP-1RAs in the nervous, cardiovascular, and endocrine systems and their correlation with metabolism, tumours and other diseases

Current and emerging biologic therapies targeting eosinophilic disorders