Clinical trials in adolescents have found GLP-1 medications can lead to significant weight loss when combined with lifestyle changes
Large-scale clinical trials and real-world studies have examined the relationship between GLP-1-based medications and cancer incidence, though it's important to note these studies were not specifically designed or powered to detect differences in cancer outcomes
Semaglutide has more long-term safety data and is often more affordable
In contrast, gestational obesity and diabetes can cause embryonic hyperinsulinemia and lead to infants that are large-for-gestational age (LGA), which is associated with a higher risk of obesity and metabolic disorders in adulthood (4, 15, 16)
adults for weight loss, according to recent survey data
Systematic review design The authors screened various electronic databases to identify clinical trials that investigated the effect of GLP-1 receptor agonists on different types of substance use disorders (alcohol, nicotine, and cocaine use disorders) in adult patients