DOI: 10.1021/ci9803381 Mann, E
Side Effects and Precautions Known Risks (Animal Studies + Anecdotal Reports) Potential for over-stimulation of neurogenesis , which is beneficial short-term but may carry unknown long-term risks Some users report: Mild headaches Irritability or emotional blunting Temporary insomnia if taken late in the day Theoretical Risk: Tumor Growth
Zhu and Li, 2021) or to hinder the translocation of pathogens, such as viruses, within the plant (Otulak-Kozie et al., 2018a, b, 2020)
By week 36, this weight loss effect was even more pronounced, increasing from 9.4% to 14.7%, while the placebo group saw a reduction of only 2.3%
Non-enrollment may indicate non-standard sourcing
Data collection in the 4 prospective cohorts was supported by a number of grants: the Netherlands Organization for Health Research and Development (ZonMw grant 89000001), the European Research Council (ERC) under the European Union Seventh Framework Program (FP/20072013)/ERC Advanced grant 291339, the Dutch Society of Physical Therapy (grant 33368), and the Dutch Brain Foundation (Hersenstichting Nederland, grant F2011(1)-25)