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In clinical trials, patients lost an average of 1517% of their body weight after 68 weeks when combined with diet and exercise

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(8) M Navarro, F Carvajal, J M Lerma-Cabrera, et al (2015) Evidence that Melanocortin Receptor Agonist Melanotan-II Synergistically Augments the Ability of Naltrexone to Blunt Binge-Like Ethanol Intake in Male C57BL/6J Mice Alcoholism, Clinical & Experimental Research, 2015 Aug, Volume 39 (Issue 8), Pages 1425-33