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Additionally, the currently approved GLP-1 RA for obesity treatment are in injectable form and some people may be reluctant to consider injectable treatments [15]

[43][44][45] Suberyl glycine is an N-acylglycine, which may indicate medium chain acyl-CoA dehydrogenase deficiency leading to a perturbation in fatty acid metabolism

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Over time, some of these early effects may diminish with adaptation, whereas reduced responsiveness to highly rewarding food cues may persist in a subset of individuals (60)