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"This large-scale analysis suggests that OSA status may act as an effect modifier in the association between GLP-1RA prescription and mortality," Fowler said

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Cox proportional hazards models were used to estimate hazard ratios (HRs)

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GLP-1RAs suppress NLRP3 inflammasome activation via attenuating the expression of NLRP3, apoptotic speck containing protein (ASC), and cleaves caspase 1 (p10) [111]

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