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PPARs can recognize a large class of endogenous ligands among which some 3 and 6-polyunsaturated fatty acids (PUFAs) and some saturated fatty acids, such as myristic acids

Electrolytes regulate nerve signals and muscle contraction

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The other works from the bottom up, mimicking a gut hormone that slows digestion, regulates blood sugar, and quietly rewires the appetite centers of the brain