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Oral supplements: can work for mild deficiency and maintenance in people who absorb B12 normally, but tend to take longer and are less reliable when absorption is impaired
Standardizing scores for each risk indicator based on the mean and standard deviation of the raw risk indicator scores is a standard statistical method to ensure comparability across participants and specialties
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Dosing is individualized, but a typical protocol titrates from a starting dose up to a target dose over 2 to 4 weeks, injected 5 days on and 2 days off, in defined cycles with scheduled breaks between them
TOP THE GUIDELINES AND PROTOCOLS ADVISORY COMMITTEE The principles of the Guidelines and Protocols Advisory Committee are to: encourage appropriate responses to common medical situations recommend actions that are sufficient and efficient, neither excessive nor deficient permit exceptions when justified by clinical circumstances Contact Information: Guidelines and Protocols Advisory Committee PO Box 9642 STN PROV GOVT Victoria BC V8W 9P1 Email: [email protected] Website: www.BCGuidelines.ca Disclaimer The Clinical Practice Guidelines (the Guidelines) have been developed by the Guidelines and Protocols Advisory Committee on behalf of the Medical Services Commission