Research in aged animals has demonstrated that NAD+ supplementation can restore DNA repair capacity to more youthful levels, with studies showing 30-50% improvements in repair efficiency following NAD+ precursor administration
Csibi A, Fendt SM, Li C, Poulogiannis G, Choo AY, Chapski DJ, Jeong SM, Dempsey JM, Parkhitko A, Morrison T, Henske EP, Haigis MC, Cantley LC, Stephanopoulos G, Yu J, Blenis J
The substantial impact of oxidative stress on sperm functionality and male fertility underscores the necessity for early detection and proactive management in infertile men
Combes, V., Guillemin, G
Interestingly, a few years ago it has been published that in flies missense mutations of the SLC25A39 homologue shawn results in accumulation of ROS as well as in mitochondrial dysfunction, synaptic defects, and neurodegeneration
Detoxification : As a key component of the body's detoxification system, glutathione helps remove harmful toxins and pollutants from the body