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Although these analyses were prespecified and hypothesis driven, the study sample size was not explicitly powered for these secondary and exploratory outcomes

N Engl J Med (2013) 369(14):131726.10.1056/NEJMoa1307684 183 WhiteWBCannonCPHellerSRNissenSEBergenstalRMBakrisGLet alAlogliptin after acute coronary syndrome in patients with type 2 diabetes