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Thomsen–Friedenreich Antigen
an α1-3-linked glucose disaccharide
This compound presents an A2 biantennary N-glycan capped with α2-6-linked sialic acid (disialo) on an Asn core
/ Fmoc-Ser(Neu5Acα(2-6)GalNAc)-OH (Peracetate
C45H54N4O20 / 970
AG142000: α-D-GalNAc-Butyl-Carboxylic Acid Pack Size:50 mg Thomsen–Friedenreich AntigenC13H23NO8 321. 32 An D N acetylgalactosamine (GalNAc) ligand equipped with a terminal carboxylic acid through a short butyl spacer. The carboxylic acid can be activated to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and reacted with amine functionalized platforms or lysine residues on proteins and peptides to form stable amide bonds. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the
