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Semaglutide, on the other hand, has been extensively studied and is approved by the FDA for weight loss

Appetite suppression, while technically a side effect, is actually the desired mechanism that drives weight loss

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doi: 10.1016/S0140-6736(23)01685-9 207 NyasuluPSTamuziJLErasmusRT

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Melanotan-1 has minimal affinity for MC4R compared to PT-141, so it shouldn't produce significant sexual arousal effects at standard dosing