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IDPs and IDRs perform functions that synergize with the roles of ordered proteins and domains (Iakoucheva et al., 2002

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However, the ability of this technique to follow the structural evolution of a protein from an unfolded to a folded state, providing insight into the flexibility of folding intermediates, was demonstrated in 1993 by Miranker et al

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5) or 7 dpf (Fig

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