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GIP acts on GIP receptors (GIPR) which are highly expressed in the pancreas, CNS, bone, and adipose tissue (Zhang et al

Since semaglutide continues suppressing appetite across days, a single day of overeating has minimal long-term impact

Benefits include: Better diabetes control Lower HbA1c Reduced insulin resistance 4

GLP-1 secretion is regulated by IL-6 signalling: a randomised, placebo-controlled study

Light physical activity like walking for 15 to 20 minutes after eating promotes gastric motility and can help move food through your system more quickly, reducing the fermentation window

This should include measurement of thyroid-stimulating hormone (TSH) and, if not previously documented, free thyroxine (free T4) levels