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4-Carboxybutyl N-acetyl-β-D-glucosaminide
producing high-avidity binding that substantially exceeds the affinity of monovalent GalNAc ligands and closely mimics the geometry of clinically validated Tri-GalNAc targeting moieties used in approved GalNAc-siRNA therapeutics
C8H16O5S / 224
the sialylation of therapeutic proteins can affect their serum half-life
2-Acetylthioethyl β-D-glucopyranoside
AG423000: β-D-Gal-Ethyl-Amine Pack Size:100 mg 4-Carboxybutyl N-acetyl-β-D-glucosaminideC8H17NO6 223. 22 A D galactose ligand equipped with an amine functionalized linker through a short ethyl spacer. The primary amine can be covalently coupled with N hydroxysuccinimide (NHS) activated esters to form stable amide bonds, providing a straightforward route to conjugate the ligand onto NHS activated molecules and surfaces. This compound provides a anomeric galactose building block for glycoconjugate synthesis, glycomimetic research, and the
