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J Neurochem 92(4):798806 Ambery P, Parker VE, Stumvoll M, Posch MG, Heise T, Plum-Moerschel L et al (2018) MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study

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If theres severe inflammation, there might be bleeding from perforation of the intestinal lining, and sometimes they could be bleeding from irritation of the colon, he says

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