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This cAMP signal is transduced downstream through both protein kinase A (PKA) and EPAC pathways

Due to the insulin resistance condition, metformin should be used as a first-line therapy combined with GLP1-RA, which show cardiovascular protective effects and intermediate to very high weight loss

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Dado que clnicamente las mculas pigmentadas no se pueden diferenciar de un melano temprano , y son lesiones poco frecuentes, se resec y analiz para diagnosticarla

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