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Additionally, honokiol preserves the phosphorylation of dynamin-related protein 1 (Drp1) at the Ser637 site and blocks its translocation to the mitochondria, which in turn prevents mitochondrial fragmentation and subsequent cell damage and death to mitigate renal injury induced by cisplatin (Mao et al., 2022)

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Complying with USP standards, it contains benzyl alcohol as a bacteriostatic preservative, allowing for repeated aseptic withdrawals without contamination

This dual interaction promotes vasodilation, improves local blood flow, and supports endothelial repair

However, our prior research did not thoroughly investigate the interplay among ferroptosis, inflammation, and oxidative stress, not to mention the realization of long-lasting and recyclable antioxidant treatment targeting the IVD microenvironment