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2020;124:104778 Vestlund J, Jerlhag E

Note that prescription options like domperidone should be used at the lowest effective dose for the shortest duration due to cardiac side effect risks, and metoclopramide is typically limited to short-term use (5 days) due to neurological adverse effects [10] For constipation, consider osmotic laxatives (e.g., macrogol) or stimulant laxatives if needed, but avoid long-term use without medical advice Do not stop semaglutide without medical advice

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According to the authors , the present trial builds on previous research by evaluating treatment-seeking participants receiving the full obesity dose of semaglutide