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NAD(+) metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus

GLP-1 agonists lower pro-inflammatory cytokines and oxidative stress

While the trials were negative clinically, presenters and discussants noted biomarker changes consistent with reduced neuroinflammation (e.g., decreases in highsensitivity CRP) and other Alzheimersrelated signalsmodest but statistically significant effects that did not yield measurable cognitive benefit

You might notice slightly reduced appetite by evening, but changes are subtle

After accounting for differences in age, body weight, other health conditions, and prior migraine treatments, researchers found people who started GLP-1 drugs were approximately 10 per cent less likely than those who started topiramate to visit the emergency department over the following year

2025;39:e153e154